Professor Alan Boobis OBE, Toxicologist, Division of Medicine, Imperial College London states that "The body’s own detoxification systems are remarkably sophisticated and versatile. They have to be, as the natural environment that we evolved in is hostile. It is remarkable that people are prepared to risk seriously disrupting these systems with unproven ‘detox’ diets, which could well do more harm than good."
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Finally, while many testimonial and anecdotal accounts exist of health improvements following a "detox", these are more likely attributable to the placebo effect; where people actually believe that they are doing something good and healthy. Yet, there is a severe lack of quantitative data. Some changes recommended in certain "detox" lifestyles are also found in mainstream medical advice (such as consuming a diet high in fruits and vegetables). These changes can often produce beneficial effects in and of themselves, and it is accordingly difficult to separate these effects from those caused by the more controversial detoxification recommendations.